Tuesday, April 30, 2013

Get kicked off Lifeline even though you still qualify too?

http://www.fcc.gov/guides/lifeline-and-link-affordable-telephone-service-income-eligible-consumers




"The FCC’s Enforcement Bureau maintains a dedicated Lifeline Fraud Tip Line –1-855-4LL-TIPS (or 1-855-455-8477), and an email address, Lifelinetips@fcc.gov – to facilitate reporting of possible fraud in the program. Callers are encouraged to provide as much detail as possible, including the name and contact information of the individuals involved and the companies they are using to receive Lifeline-supported phone service.
For information about other telecommunications issues, visit the FCC's Consumer and Governmental Affairs Bureau website, or contact the FCC's Consumer Center by calling 1-888-CALL-FCC (1-888-225-5322) voice or 1-888-TELL-FCC (1-888-835-5322) TTY; faxing 1-866-418-0232; or writing to:
Federal Communications Commission
Consumer and Governmental Affairs Bureau
Consumer Inquiries and Complaints Division
445 12th Street, SW
Washington, D.C. 20554.

Sunday, April 28, 2013

'For a Song'








'For a song'


Suze Rotolo died in February [2011]. She said on NPR in 2008 that Don Hunstein took the cover photo for “The Freewheelin’ Bob Dylan” as they were walking down Jones Street toward West Fourth Street Greenwich Village, N.Y. She interested Dylan in Arthur Rimbaud, Bertold Brecht and painting before the pressures of his fame caused her to leave in 1962, inspiring “Don’t Think Twice, its Alright.”





Happily married to producer John Porter today, in 1964 Linda Keith went through the windshield in a car crash driving back from Stonehenge. In Kris Needs’ 2004 book “Keith Richards: Before They Make Me Run” she says of Richards visiting her in the hospital: “He showed me I wasn’t a monster. I wasn’t revolting. And that was Keith.” In Mojo Magazine Keith Richards said “Ruby Tuesday” was written on a Tuesday in January 1967 because Linda had “…pissed off somewhere.”





The Brownfield (Texas) News says Buddy Holly’s high school friend Peggy Sue Gerron is again living in Lubbock, Texas after raising two sons, co-writing a book and being the first licensed female plumber in California.





Lucy Vodden (nee O’Donnell) died at 46 of lupus in 2009. On BBC Radio she said she and Julian Lennon were throwing paint at each other at a double-sided easel in their nursery school the day he painted the picture of her he called “Lucy — in the sky with diamonds.”





“Melodies are memories,” as the Five for Fighting song says.





Five for Fighting "Slice"

Bangor Daily News - Friday, June 10, 2011


'rosanna'




.

.

.

.

.

.

.















http://bangordailynews.com/2011/06/09/opinion/friday-june-10-2011-for-a-song-stick-to-the-union-electricity-sources/

-Bangor Daily News link to letter



http://www.zillow.com/homedetails/Jones-St-And-West-4th-St-Manhattan-NY-10014/2115816987_zpid/


- Jones St + 4th St. map, street view + bird's eye view link at zillow.com http://www.npr.org/player/v2/mediaPlayer.html?action=1&t=1&islist=false&id=134158270&m=134158338 Remembring Suze NPR 's Fresh Air.

Friday, April 26, 2013

Social Security Disability review meeting with Dr. Sparacio

https://plus.google.com/112400045904463207721#112400045904463207721/videos




Still won't play...you'll have to go to "videos" and and look for the one showing ceiling tiles - I apologize,  but here's "Answering Machine" to try to make up for it! :







I should also mention that around 1988 or 1989 while I was working at Carol Cable (which appears to have changed its name to General Cable and sells Carol products) and the Clark Art Institute as a night watchman, the town's building inspector threatened to condemn my father's (and my mother's family's ) house if I didn't give him a detailed plan to get a building permit just to repair the roof.

They ordered my father to come to the town hall for a meeting, and I told him that since it was my idea to repair the roof, I would go and explain. He told me to take my sister's portable tape recorder that she left with us when she got married.

I brought the tape recorder to the meeting, but since I was listening to The Replacements on my headphones, I didn't notice "Blonde on Blonde" - was playing when I had turned on my sister's tape recorder.

The town manager order the chief of police to get my father, and they brought him in a police car to the meeting.

I noticed the tape player was not recording, and set it correctly.

The building inspector - well, I'll have to digress - who looked and sounded very similar to Governor LePage, and also the Rochester, NY state employment agency councelor who wouldn't give me the addresses of jobs available when I was living in the woods next to a golf course by the Rochester International Airport (we were only allowed to bring 2 potential jobs to the counselors at a time) for the whole 2 months I lived there in the Fall of 1986 -  the LePagesque building inspector came into to the meeting room and the town manager or someone asked him a question, and the building inspector almost shouted: "not with that thing there!..." while pointing at the tape recorder.

Oh, yes. I forgot to mention that the first Social Security disability review that I had in around 2006 was performed by Social Security, while for some reason, this review was performed by the State of Maine Department of Health and Human Services.



Thursday, April 25, 2013


Atypical Antipsychotic Drugs and Diabetes Mellitus in the US Food and Drug Administration Adverse Event Database: A Systematic Bayesian Signal Detection Analysis

Ross A. Baker, Andrei Pikalov, Quynh-Van Tran, Tatyana Kremenets, Ramin B. Arani, P. Murali Doraiswamy
Disclosures
Psychopharmacol Bull. 2009;42(1):1-21. 

Abstract and Introduction

Abstract

Background: Prior literature suggests that the risk of diabetes-related adverse events (DRAEs) differs between atypical antipsychotics. The present study evaluated the potential association between atypical antipsychotics or haloperidol and diabetes using data from the FDA AERS database.

Methods: Analysis of AERS data was conducted for clozapine, risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole or haloperidol with 24 DRAEs from the Medical Dictionary for Regulatory Activities using a Multi-item Gamma Poisson Shrinker (MGPS) data-mining algorithm. Using MGPS, adjusted reporting ratios (Empiric Bayes Geometric Mean or EBGM) and 90% confidence intervals (CIs; EB05–EB95) were calculated to estimate the degree of drug–event association relative to all drugs and events. Logistic regression odds ratios and 90% CIs (LR05–LR95) were calculated for diabetes mellitus events.

Results: All six atypicals had an EB05 ≥ 2 for at least one DRAE. The most common event was diabetes mellitus (2,784 cases). Adjusted reporting ratios (CIs) for diabetes mellitus were: olanzapine 9.6 (9.2–10.0; 1306 cases); risperidone 3.8 (3.5–4.1; 447 cases); quetiapine 3.5 (3.2–3.9; 283 cases); clozapine 3.1 (2.9–3.3; 464 cases); ziprasidone 2.4 (2.0–2.9; 74 cases); aripiprazole 2.4 (1.9–2.9; 71 cases); haloperidol 2.0 (1.7–2.3; 139 cases). Logistic regression odds ratios agreed with adjusted reporting ratios.

Conclusions: In the AERS database, lower associations with DRAEs were seen for haloperidol, aripiprazole and ziprasidone, and higher associations were seen for olanzapine, risperidone, clozapine and quetiapine. Our findings support differential risk of diabetes across atypical antipsychotics, reinforcing the need for metabolic monitoring of patients taking antipsychotics.

Introduction

The risk of diabetes is markedly higher (two- to three-fold) in patients with schizophrenia compared with the general population,[1] and evidence suggests a similar increased incidence of diabetes in patients with bipolar disorder and schizoaffective disorder.[2,3] The main potential metabolic concerns in addition to the risk of developing type II diabetes are the risk for cardiovascular disease (CVD) and shorter life-expectancy. Mortality among patients with schizophrenia is higher than among the general population, and CVD accounts for a significant proportion of this excess mortality.[4-6] Furthermore, metabolic syndrome (a constellation of obesity, insulin resistance, dyslipidemia, impaired glucose tolerance and hypertension) is also highly prevalent in psychiatric patients[7,8] and may further increase CVD risk. Early, effective monitoring of metabolic side effects is essential to minimize their long-term impact. To date, awareness and monitoring of these effects has been less than optimal;[9] thus, a need exists to establish clearly the rate of such side effects and their association with various treatment paradigms.
Atypical antipsychotics are used to treat schizophrenia and bipolar disorder, and are under investigation for the treatment of many other mood and anxiety disorders. They have largely supplanted older typical agents in many settings because of some advantages over older antipsychotics, such as a reduced propensity for extrapyramidal symptoms.[10] However, in recent years, suggestions of an increased occurrence of diabetes and other metabolic disturbances with some atypical antipsychotics agents, such as clozapine and olanzapine, have raised significant concerns.[11-16] A number of prior studies have documented abnormal glucose metabolism (impaired glucose tolerance, diabetes and ketoacidosis) during treatment with clozapine, olanzapine, risperidone and quetiapine.[11,17-22] Although prospective, controlled comparisons of multiple agents are limited, the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study showed that olanzapine was associated with greater increases in weight gain and measures of glucose and lipids.[23] Growing evidence indicates a lower likelihood of metabolic and diabetes-related adverse events with the newer atypical agents, ziprasidone and aripiprazole.[14,22,24] In addition, both agents have shown a potential to reverse abnormal glucose metabolism related to treatment with other antipsychotics.[24,25,26]
Although the underlying cause of abnormalities in glucose metabolism observed during antipsychotic treatment is unclear, one possible mechanism may be increased insulin resistance as a result of antipsy-chotic-induced weight gain.[27] Indeed, the relationship between excessive weight gain and increased risk of diabetes in the general population is well established,[28] and the atypical antipsychotics associated with the greatest risk of diabetes (clozapine and olanzapine) have been associated with the highest risk of weight gain.[12] Moreover, direct effects of atypical antipsychotics on insulin secretion, as well as other mechanisms, have not been discounted.[29,30]
Given the contribution of diabetes to CVD, and the observed excess mortality in patients with psychiatric disorders, there is great interest in further clarification of the differential effects of atypical antipsychotic agents on diabetes-related adverse eve



nts (DRAEs), ranging from new-onset hyperglycemia to life-threatening ketoacidosis. Therefore, the objective of this present study was to evaluate the potential association between the atypical antipsychotics or haloperidol and diabetes using data from the US Food and Drug Administration (FDA) Adverse Event Reporting System (AERS). The AERS database is a post-marketing surveillance safety database for all approved drugs and therapeutic biological products that aims to monitor and improve drug safety.
Section 1 of 5

  1. Suvisaari J, Perala J, Saarni SI, Harkanen T, Pirkola S, Joukamaa M, Koskinen S, Lonnqvist J, Reunanen A. Type 2 diabetes among persons with schizophrenia and other psychotic disorders in a general population survey Eur Arch Psychiatry Clin Neurosci. 2007;258(3):129–136.
  2. Regenold WT, Thapar RK, Marano C, Gavirneni S, Kondapavuluru PV. Increased prevalence of type 2 diabetes mellitus among psychiatric inpatients with bipolar I affective and schizoaffective disorders independent of psychotropic drug use. J Affect Disord. 2002;70(1):19–26.
  3. van Winkel R, De Hert M, Van Eyck D, Hanssens L, Wampers M, Scheen A, Peuskens J. Screening for diabetes and other metabolic abnormalities in patients with schizophrenia and schizoaffective disorder: evaluation of incidence and screening methods. J Clin Psychiatry. 2006;67(10):1493–1500.
  4. Barnett A, Mackin P, Chaudhry I, Farooqi A, Gadsby R, Heald A, Hill J, Millar H, Peveler R, Rees A, Singh V, Taylor D, Vora J, Jones P Minimising metabolic and cardiovascular risk in schizophrenia: diabetes, obesity and dyslipidaemia. J Psychopharmacol OnlineFirst, published on April 19th, 2007;21(4):357–373.
  5. Hennekens CH, Hennekens AR, Hollar D, Casey DE. Schizophrenia and increased risks of cardiovascular disease. Am Heart J. 2005;150(6):1115–1121.
  6. Henderson DC. Schizophrenia and comorbid metabolic disorders. J Clin Psychiatry. 2005;66 (Suppl 6):11–20.
  7. Fagiolini A, Frank E, Scott JA, Turkin S, Kupfer DJ. Metabolic syndrome in bipolar disorder: findings from the Bipolar Disorder Center for Pennsylvanians. Bipolar Disord. 2005;7(5):424–430.
  8. McEvoy JP, Meyer JM, Goff DC, Nasrallah HA, Davis SM, Sullivan L, Meltzer HY, Hsiao J, Scott Stroup T, Lieberman JA. Prevalence of the metabolic syndrome in patients with schizophrenia: Baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III. Schizophr Res. 2005;80:19-32.
  9. Haupt D, Rosenblatt L, Kim E, Baker R, Whitehead R, Newcomer J. Prevalence and Predictors of Lipid and Glucose Monitoring among Commercially Insured Patients Treated with Second-Generation Antipsychotic Agents.American Journal of Psychiatry; in press. 2008.
  10. Tandon R. Safety and tolerability: how do newer generation "atypical" antipsychotics compare? Psychiatr Q.2002;73(4):297–311.
  11. Koller EA, Doraiswamy PM. Olanzapine-associated diabetes mellitus. Pharmacotherapy. 2002;22(7):841–852.
  12. ADA/APA/AACE/NAASO. Consensus development conference on antipsychotic drugs and obesity and diabetes. American Diabetes Association; American Psychiatric Association; American Association of Clinical Endocrinologists; North American Association for the Study of Obesity Diabetes Care. 2004;27(2):596–601.
  13. Lambert BL, Cunningham FE, Miller DR, Dalack GW, Hur K. Diabetes risk associated with use of olanzapine, quetiapine, and risperidone in veterans health administration patients with schizophrenia. Am J Epidemiol.2006;164(7):672–681.
  14. Newcomer JW. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs. 2005;19(Suppl 1):1–93.
  15. Ramaswamy K, Masand PS, Nasrallah HA. Do certain atypical antipsychotics increase the risk of diabetes? A critical review of 17 pharmacoepidemiologic studies. Ann Clin Psychiatry. 2006;18(3):183–194.
  16. Citrome L. Olanzapine: interpreting the label change. Int J Clin Pract. 2007;61(12):1960–1962.
  17. Hedenmalm K, Hagg S, Stahl M, Mortimer O, Spigset O. Glucose intolerance with atypical antipsychotics. Drug Saf. 2002;25(15):1107–1116.
  18. Henderson DC, Cagliero E, Copeland PM, Borba CP, Evins E, Hayden D, Weber MT, Anderson EJ, Allison DB, Daley TB, Schoenfeld D, Goff DC. Glucose metabolism in patients with schizophrenia treated with atypical antipsychotic agents: a frequently sampled intravenous glucose tolerance test and minimal model analysis. Arch Gen Psychiatry. 2005;62(1):19–28.
  19. Koller E, Schneider B, Bennett K, Dubitsky G. Clozapine-associated diabetes. Am J Med. 2001;111(9):716–723.
  20. Koller EA, Cross JT, Doraiswamy PM, Schneider BS. Risperidone-associated diabetes mellitus: a pharmacovigilance study. Pharmacotherapy. 2003;23(6):735–744.
  21. Koller EA, Weber J, Doraiswamy PM, Schneider BS. A survey of reports of quetiapine-associated hyperglycemia and diabetes mellitus. J Clin Psychiatry. 2004;65(6):857–863.
  22. Scheen AJ, De Hert MA. Abnormal glucose metabolism in patients treated with antipsychotics. Diabetes Metab.2007;33:169-175.
  23. Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, Keefe RS, Davis SM, Davis CE, Lebowitz BD, Severe J, Hsiao JK. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med. 2005;353(12):1209–1223.
  24. Montes JM, Rodriguez JL, Balbo E, Sopelana P, Martin E, Soto JA, Delgado JF, Diez T, Villardaga I. Improvement in antipsychotic-related metabolic disturbances in patients with schizophrenia switched to ziprasidone. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31(2):383–388.
  25. De Hert M, Hanssens L, van Winkel R, Wampers M, Van Eyck D, Scheen A, Peuskens J. Reversibility of antipsychotic treatment-related diabetes in patients with schizophrenia: a case series of switching to aripiprazole.Diabetes Care. 2006;29(10):2329–2330.
  26. De Hert M, Hanssens L, van Winkel R, Wampers M, Van Eyck D, Scheen A, Peuskens J. A Case Series: Evaluation of the Metabolic Safety of Aripiprazole. Schizophr Bull. 2007;33(33):823–830.
  27. Albaugh VL, Henry CR, Bello NT, Hajnal A, Lynch SL, Halle B, Lynch CJ. Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents. Obesity (Silver Spring). 2006;14(1):36-51.
  28. ADA. Position statements and ADA statements. Diabetes Care. 2006;29(Suppl 1):S75–77.
  29. Houseknecht KL, Robertson AS, Zavadoski W, Gibbs EM, Johnson DE , Rollema H. Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: implications for adverse metabolic effects.Neuropsychopharmacology. 2007;32(2):289–297.
  30. Johnson DE, Yamazaki H, Ward KM, Schmidt AW, Lebel WS, Treadway JL, Gibbs EM, Zawalich WS, Rollema H. Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from peri-fused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia. Diabetes. 2005;54(5):1552–1558.
  31. Rodriguez EM, Staffa JA, Graham DJ. The role of databases in drug postmarketing surveillance.Pharmacoepidemiol Drug Saf. 2001;10(5):407–410.
  32. DuMouchel W. Bayesian Data Mining in Large Frequency Tables, With an Application to the FDA Spontaneous Reporting System. The American Statistician. 1999;53:177-190.
  33. Hastie T, Tibshirani R, Friedman J.The Elements of Statistical Learning: Data Mining, Inference and Prediction. New York: Springer, 2001.
  34. Hauben M, Horn S, Reich L. Potential use of data-mining algorithms for the detection of 'surprise' adverse drug reactions. Drug Saf. 2007;30(2):143–155.
  35. Szarfman A, Machado SG, O'Neill RT Use of screening algorithms and computer systems to efficiently signal higher-than-expected combinations of drugs and events in the US FDA's spontaneous reports database. Drug Saf.2002;25(6):381–392.
  36. DuMouchel W, Fram D, Yang X, Mahmoud RA, Grogg AL, Engelhart L, Ramaswamy K. Antipsychotics, glycemic disorders, and life-threatening diabetic events: a Bayesian data-mining analysis of the FDA adverse event reporting system (1968–2004). Ann Clin Psychiatry. 2008;20(1):21–31.
  37. Buse JB, Cavazzoni P, Hornbuckle K, Hutchins D, Breier A, Jovanovic L. A retrospective cohort study of diabetes mellitus and antipsychotic treatment in the United States./ Clin Epidemiol. 2003;56(2):164-170.
  38. McQuade RD, Stock E, Marcus R, Jody D, Gharbia NA, Vanveggel S, Archibald D, Carson WH. A comparison of weight change during treatment with olanzapine or aripiprazole: results from a randomized, double-blind study./Clin Psychiatry. 2004;65(Suppl 18):47–56.
  39. Simpson GM, Glick ID, Weiden PJ, Romano SJ , Siu CO. Randomized, controlled, double-blind mul-ticenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder. Am J Psychiatry. 2004;161(10):1837–1847.
  40. Fegert JM. [Specific features and problems in the pharmacotherapy of schizophrenic psychoses in children and adolescents]. Z Arztl Fortbild Qualitatssich. 2002;96(9):597–603.
  41. Hugtenburg JG, Heerdink ER, Tso YH. Psychoactive drug prescribing by Dutch child and adolescent psychiatrists. Acta Paediatr. 2005;94(10):1484–1487.
  42. Medco Health Solutions.Growth in medication use in children—2001–2006. Franklin Lakes, NJ: Medco Health Solutions, 2007.
  43. Zito JM, Safer DJ, dosReis S, Gardner JF, Boles M, Lynch FTrends in the prescribing of psychotropic medications to preschoolers. Jama. 2000;283(8):1025–1030.
  44. Zito JM, Safer DJ, Valluri S, Gardner JF, Korelitz JJ, Mattison DR. Psychotherapeutic medication prevalence in Medicaid-insured preschoolers. J Child Adolesc Psychopharmacol. 2007;17(2):195–203.
  45. Szarfman A, Tonning JM, Levine JG, Doraiswamy PM. Atypical antipsychotics and pituitary tumors: a pharmacovigilance study. Pharmacotherapy. 2006;26(6):748–758.



    Schizophrenia: Natural Remedies

    Home Remedies for Schizophrenia | Top 10 Home Remedies











    Free Skype internet calls and cheap calls to phones online - Skype

    Schizophrenia: Natural Remedies





Wednesday, April 24, 2013

"Madness"



                                                             





  1. Schizophrenia and comorbid metabolic disorders.





  2. Haupt D, Rosenblatt L, Kim E, Baker R, Whitehead R, Newcomer J. Prevalence and Predictors of Lipid and Glucose Monitoring among Commercially Insured Patients Treated with Second-Generation Antipsychotic Agents.American Journal of Psychiatry; in press. 2008.
  3. Tandon R. Safety and tolerability: how do newer generation "atypical" antipsychotics compare? Psychiatr Q.2002;73(4):297–311.
  4. Koller EA, Doraiswamy PM. Olanzapine-associated diabetes mellitus. Pharmacotherapy. 2002;22(7):841–852.
  5. ADA/APA/AACE/NAASO. Consensus development conference on antipsychotic drugs and obesity and diabetes. American Diabetes Association; American Psychiatric Association; American Association of Clinical Endocrinologists; North American Association for the Study of Obesity Diabetes Care. 2004;27(2):596–601.
  6. Lambert BL, Cunningham FE, Miller DR, Dalack GW, Hur K. Diabetes risk associated with use of olanzapine, quetiapine, and risperidone in veterans health administration patients with schizophrenia. Am J Epidemiol.2006;164(7):672–681.
  7. Newcomer JW. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs. 2005;19(Suppl 1):1–93.
  8. Ramaswamy K, Masand PS, Nasrallah HA. Do certain atypical antipsychotics increase the risk of diabetes? A critical review of 17 pharmacoepidemiologic studies. Ann Clin Psychiatry. 2006;18(3):183–194.
  9. Citrome L. Olanzapine: interpreting the label change. Int J Clin Pract. 2007;61(12):1960–1962.
  10. Hedenmalm K, Hagg S, Stahl M, Mortimer O, Spigset O. Glucose intolerance with atypical antipsychotics. Drug Saf. 2002;25(15):1107–1116.
  11. Henderson DC, Cagliero E, Copeland PM, Borba CP, Evins E, Hayden D, Weber MT, Anderson EJ, Allison DB, Daley TB, Schoenfeld D, Goff DC. Glucose metabolism in patients with schizophrenia treated with atypical antipsychotic agents: a frequently sampled intravenous glucose tolerance test and minimal model analysis. Arch Gen Psychiatry. 2005;62(1):19–28.
  12. Koller E, Schneider B, Bennett K, Dubitsky G. Clozapine-associated diabetes. Am J Med. 2001;111(9):716–723.
  13. Koller EA, Cross JT, Doraiswamy PM, Schneider BS. Risperidone-associated diabetes mellitus: a pharmacovigilance study. Pharmacotherapy. 2003;23(6):735–744.
  14. Koller EA, Weber J, Doraiswamy PM, Schneider BS. A survey of reports of quetiapine-associated hyperglycemia and diabetes mellitus. J Clin Psychiatry. 2004;65(6):857–863.
  15. Scheen AJ, De Hert MA. Abnormal glucose metabolism in patients treated with antipsychotics. Diabetes Metab.2007;33:169-175.
  16. Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, Keefe RS, Davis SM, Davis CE, Lebowitz BD, Severe J, Hsiao JK. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med. 2005;353(12):1209–1223.
  17. Montes JM, Rodriguez JL, Balbo E, Sopelana P, Martin E, Soto JA, Delgado JF, Diez T, Villardaga I. Improvement in antipsychotic-related metabolic disturbances in patients with schizophrenia switched to ziprasidone. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31(2):383–388.
  18. De Hert M, Hanssens L, van Winkel R, Wampers M, Van Eyck D, Scheen A, Peuskens J. Reversibility of antipsychotic treatment-related diabetes in patients with schizophrenia: a case series of switching to aripiprazole.Diabetes Care. 2006;29(10):2329–2330.
  19. De Hert M, Hanssens L, van Winkel R, Wampers M, Van Eyck D, Scheen A, Peuskens J. A Case Series: Evaluation of the Metabolic Safety of Aripiprazole. Schizophr Bull. 2007;33(33):823–830.
  20. Albaugh VL, Henry CR, Bello NT, Hajnal A, Lynch SL, Halle B, Lynch CJ. Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents. Obesity (Silver Spring). 2006;14(1):36-51.
  21. ADA. Position statements and ADA statements. Diabetes Care. 2006;29(Suppl 1):S75–77.
  22. Houseknecht KL, Robertson AS, Zavadoski W, Gibbs EM, Johnson DE , Rollema H. Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: implications for adverse metabolic effects.Neuropsychopharmacology. 2007;32(2):289–297.
  23. Johnson DE, Yamazaki H, Ward KM, Schmidt AW, Lebel WS, Treadway JL, Gibbs EM, Zawalich WS, Rollema H. Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from peri-fused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia. Diabetes. 2005;54(5):1552–1558.
  24. Rodriguez EM, Staffa JA, Graham DJ. The role of databases in drug postmarketing surveillance.Pharmacoepidemiol Drug Saf. 2001;10(5):407–410.
  25. DuMouchel W. Bayesian Data Mining in Large Frequency Tables, With an Application to the FDA Spontaneous Reporting System. The American Statistician. 1999;53:177-190.
  26. Hastie T, Tibshirani R, Friedman J.The Elements of Statistical Learning: Data Mining, Inference and Prediction. New York: Springer, 2001.
  27. Hauben M, Horn S, Reich L. Potential use of data-mining algorithms for the detection of 'surprise' adverse drug reactions. Drug Saf. 2007;30(2):143–155.
  28. Szarfman A, Machado SG, O'Neill RT Use of screening algorithms and computer systems to efficiently signal higher-than-expected combinations of drugs and events in the US FDA's spontaneous reports database. Drug Saf.2002;25(6):381–392.
  29. DuMouchel W, Fram D, Yang X, Mahmoud RA, Grogg AL, Engelhart L, Ramaswamy K. Antipsychotics, glycemic disorders, and life-threatening diabetic events: a Bayesian data-mining analysis of the FDA adverse event reporting system (1968–2004). Ann Clin Psychiatry. 2008;20(1):21–31.
  30. Buse JB, Cavazzoni P, Hornbuckle K, Hutchins D, Breier A, Jovanovic L. A retrospective cohort study of diabetes mellitus and antipsychotic treatment in the United States./ Clin Epidemiol. 2003;56(2):164-170.
  31. McQuade RD, Stock E, Marcus R, Jody D, Gharbia NA, Vanveggel S, Archibald D, Carson WH. A comparison of weight change during treatment with olanzapine or aripiprazole: results from a randomized, double-blind study./Clin Psychiatry. 2004;65(Suppl 18):47–56.
  32. Simpson GM, Glick ID, Weiden PJ, Romano SJ , Siu CO. Randomized, controlled, double-blind mul-ticenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder. Am J Psychiatry. 2004;161(10):1837–1847.
  33. Fegert JM. [Specific features and problems in the pharmacotherapy of schizophrenic psychoses in children and adolescents]. Z Arztl Fortbild Qualitatssich. 2002;96(9):597–603.
  34. Hugtenburg JG, Heerdink ER, Tso YH. Psychoactive drug prescribing by Dutch child and adolescent psychiatrists. Acta Paediatr. 2005;94(10):1484–1487.
  35. Medco Health Solutions.Growth in medication use in children—2001–2006. Franklin Lakes, NJ: Medco Health Solutions, 2007.
  36. Zito JM, Safer DJ, dosReis S, Gardner JF, Boles M, Lynch FTrends in the prescribing of psychotropic medications to preschoolers. Jama. 2000;283(8):1025–1030.
  37. Zito JM, Safer DJ, Valluri S, Gardner JF, Korelitz JJ, Mattison DR. Psychotherapeutic medication prevalence in Medicaid-insured preschoolers. J Child Adolesc Psychopharmacol. 2007;17(2):195–203.
  38. Szarfman A, Tonning JM, Levine JG, Doraiswamy PM. Atypical antipsychotics and pituitary tumors: a pharmacovigilance study. Pharmacotherapy. 2006;26(6):748–758

Tuesday, April 23, 2013

Hi Chief Bresett, it was Science Daily!


whiteroseleaflets


whiteroseleaflets


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